Combined optical and electrochemical analysis of protein binding with ITO-coated lossy-mode resonance sensor

Marcin Koba , Dariusz Burnat , Katarzyna Szot-Karpińska , Petr Sezemsky , Vitezslav Stranak , Robert Bogdanowicz , Joanna Niedziółka-Jönsson , Mateusz Jakub Śmietana

Abstract

This work discuses indium tin oxide (ITO) coated optical fiber lossy-mode resonance (LMR) sensor working in an electrochemical setup for monitoring of protein binding to the sensor’s surface. The binding mechanism has been observed simultaneously in optical and electrochemical domain. The combined measurement was enabled by the electrically conductive ITO overlay. In the experiment, biotin molecules have been used to test the collective optical and electrochemical setup and to illustrate the binding effect. It has been shown that the effect is observed in the investigated domains at applied potential, and the qualitative comparison shows high resemblance of the outcome.
Author Marcin Koba
Marcin Koba,,
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, Dariusz Burnat (FEIT / MO)
Dariusz Burnat,,
- The Institute of Microelectronics and Optoelectronics
, Katarzyna Szot-Karpińska
Katarzyna Szot-Karpińska,,
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, Petr Sezemsky
Petr Sezemsky,,
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, Vitezslav Stranak
Vitezslav Stranak,,
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, Robert Bogdanowicz - Gdańsk University of Technology (PG)
Robert Bogdanowicz,,
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, Joanna Niedziółka-Jönsson
Joanna Niedziółka-Jönsson,,
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, Mateusz Jakub Śmietana (FEIT / MO)
Mateusz Jakub Śmietana,,
- The Institute of Microelectronics and Optoelectronics
Pages1-4
Publication size in sheets0.5
Article number111991E
Book Kalli Kyriacos, Brambilla Gilberto, O'Keeffe Sinéad (eds.): Seventh European Workshop on Optical Fibre Sensors, no. 11199, 2019, SPIE - The International Society for Optics and Photonics, ISBN 9781510631236, 500 p., DOI:10.1117/12.2550861
1119901.pdf / 457.64 KB / No licence information
Keywords in EnglishSensors; Electrodes; Proteins; Ocean optics; Biological research; Fiber optics sensors; Optical testing
DOIDOI:10.1117/12.2540849
URL https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11199/111991E/Combined-optical-and-electrochemical-analysis-of-protein-binding-with-ITO/10.1117/12.2540849.full
Projectx. Project leader: Śmietana Mateusz Jakub, , Phone: (22) 234 63 64, start date 20-05-2015, planned end date 19-05-2019, IMiO/2015/NCN/2, Implemented
WEiTI Projects financed by NSC [Projekty finansowane przez NCN]
DIAMSEC-ultra-sensitive sensory platform for rapid detection of epidemiological and pandemic threats. Project leader: Śmietana Mateusz Jakub, , Phone: (22) 234 63 64, application date 04-11-2016, start date 01-06-2017, planned end date 31-05-2020, MO/2016/7, Implemented
WEiTI Projects financed by NCRD [Projekty finansowane przez NCBiR (NCBR)]
Languageen angielski
Score (nominal)0
Score sourceconferenceList
ScoreMinisterial score = 0.0, 22-06-2020, ChapterFromConference
Publication indicators WoS Citations = 0; Scopus Citations = 0
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