Determination of mercury cation using electrode modified with phosphorothioate oligonucleotide
Agnieszka Bala , Łukasz Górski
AbstractA novel electrochemical biosensor for the determination of mercury ion is described. The receptor layer was formed on glassy carbon electrode by adsorption of phosphorothioate oligonucleotide (PTO). The presence of sulfur atom in the backbone of modified nucleotide allows for strong interaction with Hg2+. The optimized sensor distinguishes itself with high selectivity towards mercury ions and lower detection limit of 2.34 × 10-11 mol L-1. For tested PTO sequence, it was possible to determine the linear response in the Hg2+ concentration range of 10-11-10-7 mol L-1.
|Journal series||Sensors and Actuators B - Chemical, ISSN 0925-4005|
|Publication size in sheets||0.5|
|Keywords in English||Electrochemical sensor; Metal ion determination; Phosphorothioate oligonucleotide|
|ASJC Classification||; ; ; ; ; ;|
|Score|| = 40.0, 05-09-2019, ArticleFromJournal|
= 40.0, 05-09-2019, ArticleFromJournal
|Publication indicators||= 5; : 2016 = 1.463; : 2016 = 5.401 (2) - 2016=4.855 (5)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.