Determination of mercury cation using electrode modified with phosphorothioate oligonucleotide

Agnieszka Bala , Łukasz Górski


A novel electrochemical biosensor for the determination of mercury ion is described. The receptor layer was formed on glassy carbon electrode by adsorption of phosphorothioate oligonucleotide (PTO). The presence of sulfur atom in the backbone of modified nucleotide allows for strong interaction with Hg2+. The optimized sensor distinguishes itself with high selectivity towards mercury ions and lower detection limit of 2.34 × 10-11 mol L-1. For tested PTO sequence, it was possible to determine the linear response in the Hg2+ concentration range of 10-11-10-7 mol L-1.
Author Agnieszka Bala ZMB
Agnieszka Bala,,
- Department Of Microbioanalytics
, Łukasz Górski ZMB
Łukasz Górski,,
- Department Of Microbioanalytics
Journal seriesSensors and Actuators B - Chemical, ISSN 0925-4005
Issue year2016
Publication size in sheets0.5
Keywords in EnglishElectrochemical sensor; Metal ion determination; Phosphorothioate oligonucleotide
Languageen angielski
1-s2.0-S0925400516302520-main.pdf 796.54 KB
Score (nominal)40
ScoreMinisterial score = 40.0, 28-11-2017, ArticleFromJournal
Ministerial score (2013-2016) = 40.0, 28-11-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2016 = 5.401 (2) - 2016=4.855 (5)
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