Silicon-based gold transducers for DNA biosensors
Ł. Górski , Robert Ziółkowski , Elżbieta Malinowska , Piotr Prokaryn , M. Zaborowski
AbstractSilicon-based chips with vacuum deposited gold electrode were tested as transducers for the development of DNA-modified biosensors. It was found that these structures are superior over commercially available transducers, mainly due to perfectly smooth surface of gold working electrode. This was confirmed with microscopic and electrochemical experiments. Obtained transducers were modified with oligonucleotide self-assembled monolayer. These sensors were shown to detect chosen DNA sequence with the employment of methylene blue as a redox marker. The same sensors were used to determine UO22+ cation, however these efforts were unsuccessful.
|Journal series||BIODEVICES 2011 - Proceedings of the International Conference on Biomedical Electronics and Devices, (0 pkt)|
|Keywords in English||voltammetry; vacuum deposited gold; DNA biosensors; monolayers|
|Publication indicators||= 0|
|Citation count*||1 (2015-08-08)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.