Silicon-based gold transducers for DNA biosensors

Ł. Górski , Robert Ziółkowski , Elżbieta Malinowska , Piotr Prokaryn , M. Zaborowski

Abstract

Silicon-based chips with vacuum deposited gold electrode were tested as transducers for the development of DNA-modified biosensors. It was found that these structures are superior over commercially available transducers, mainly due to perfectly smooth surface of gold working electrode. This was confirmed with microscopic and electrochemical experiments. Obtained transducers were modified with oligonucleotide self-assembled monolayer. These sensors were shown to detect chosen DNA sequence with the employment of methylene blue as a redox marker. The same sensors were used to determine UO22+ cation, however these efforts were unsuccessful.
Author Ł. Górski
Ł. Górski,,
-
, Robert Ziółkowski (FC / IBC / DM)
Robert Ziółkowski,,
- Department Of Microbioanalytics
, Elżbieta Malinowska (FC / IBC / DM)
Elżbieta Malinowska,,
- Department Of Microbioanalytics
, Piotr Prokaryn
Piotr Prokaryn,,
-
, M. Zaborowski
M. Zaborowski,,
-
Journal seriesBIODEVICES 2011 - Proceedings of the International Conference on Biomedical Electronics and Devices, (0 pkt)
Issue year2011
Pages146-149
Keywords in Englishvoltammetry; vacuum deposited gold; DNA biosensors; monolayers
Internal identifier4360
Languageen angielski
Score (nominal)0
Publication indicators WoS Citations = 0
Citation count*1 (2015-08-08)
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