Novel approach to control drug release and adherence of PLA based implant coatings

Emilia Choińska , Wojciech Święszkowski

Abstract

The typical approach to control drug release from polymeric implant coatings is based on modifying composition and molecular weight of carrier or geometric parameters of the system [1]. In such DDS also the proper adhesion of polymer to substrate have to be provided. Usually it is done by increasing of contact area (eg. surface development), or chemical treatment of substrate (eg, silanization, or phosphating) [2]. In this work novel approach, based on changing of macromolecular structure of PLA, is presented.
Author Emilia Choińska ZPM
Emilia Choińska,,
- Division of Materials Design
, Wojciech Święszkowski ZPM
Wojciech Święszkowski,,
- Division of Materials Design
Journal seriesEuropean Cells & Materials, ISSN 1473-2262
Issue year2016
Vol32
Nosuppl. 3
Pages46-47
Publication size in sheets0.3
ConferenceeCM XVII: Stem Cells, Bone Fixation, Repair & Regeneration (ECM), 20-06-2016 - 23-06-2016, Davos, Szwajcaria
Keywords in Polishpolilaktydy, uwalnianie leków, powłoki polimerowe
Keywords in Englishpolylactides, drugs release, polymeric coatings
URL http://www.ecmjournal.org/journal/supplements/vol032supp03/pdf/Vol032Supp03046.pdf
Languageen angielski
File
2016 Choinska et al. drug release eCM p46.pdf 459.18 KB
Score (nominal)45
ScoreMinisterial score = 40.0, 28-11-2017, ArticleFromJournal
Ministerial score (2013-2016) = 45.0, 28-11-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2016 = 3.343 (2) - 2016=4.803 (5)
Citation count*0 (2018-06-13)
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