Novel approach to control drug release and adherence of PLA based implant coatings
Emilia Choińska , Wojciech Święszkowski
AbstractThe typical approach to control drug release from polymeric implant coatings is based on modifying composition and molecular weight of carrier or geometric parameters of the system . In such DDS also the proper adhesion of polymer to substrate have to be provided. Usually it is done by increasing of contact area (eg. surface development), or chemical treatment of substrate (eg, silanization, or phosphating) . In this work novel approach, based on changing of macromolecular structure of PLA, is presented.
|Journal series||European Cells & Materials, ISSN 1473-2262|
|Publication size in sheets||0.3|
|Conference||eCM XVII: Stem Cells, Bone Fixation, Repair & Regeneration (ECM), 20-06-2016 - 23-06-2016, Davos, Szwajcaria|
|Keywords in Polish||polilaktydy, uwalnianie leków, powłoki polimerowe|
|Keywords in English||polylactides, drugs release, polymeric coatings|
|Score|| = 40.0, 28-11-2017, ArticleFromJournal|
= 45.0, 28-11-2017, ArticleFromJournal
|Publication indicators||: 2016 = 3.343 (2) - 2016=4.803 (5)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.