Advanced A549 and MRC-5 3D spheroid culture in microfluidic system

Agnieszka Żuchowska , Elżbieta Jastrzębska , Michał Chudy , Arur Dybko , Zbigniew Brzózka

Abstract

In this paper, a microfluidic system for long-term spheroids culture and analysis is presented. Lung cancer and normal cells were cultured in an array of microwells for 10 days. The construction of the microsystem enabled observation of morphological spheroid changes. Both cancer and normal spheroids characterized by high cells viability which was confirmed by spektrofluorimetric and microscopic measurements.

Author Agnieszka Żuchowska (FC / CMB)
Agnieszka Żuchowska,,
- Chair of Medical Biotechnology
, Elżbieta Jastrzębska (FC / CMB)
Elżbieta Jastrzębska,,
- Chair of Medical Biotechnology
, Michał Chudy (FC / CMB)
Michał Chudy,,
- Chair of Medical Biotechnology
, Arur Dybko - [Warsaw University of Technology (PW)]
Arur Dybko,,
-
- Politechnika Warszawska
, Zbigniew Brzózka (FC / CMB)
Zbigniew Brzózka,,
- Chair of Medical Biotechnology
Journal series20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Issue year2016
Pages437-438
Languageen angielski
Score (nominal)0
Score sourcejournalList
ScoreMinisterial score = 0.0, 06-12-2019, ArticleFromJournal
Ministerial score (2013-2016) = 0.0, 06-12-2019, ArticleFromJournal
Publication indicators Scopus Citations = 0
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