Investigation of the BMP-2 adsorption to different solvent-treated 3D PCL scaffolds
Alicja Kosik-Kozioł , Vaquette Cedryck , Graham Elizabeth , Adrian Chlanda , Kumar Sudhees , Ivanovski Saso , Wojciech Święszkowski , Hutmacher Dietmar
AbstractThe application of bone morphogenic proteins (BMPs) is a prominent area of research for application in bone tissue engineering. This biological protein is generally combined with a gel or a collagenous carrier to facilitate its delivery. However, this results in poorly controlling the release of the bioactive cue potentially leading to significant adverse effects. A novel strategy involves the absorption of the BMP onto a biomaterial scaffold in order to alter the release kinetic. In this study, we investigated the impact of surface modification of polycaprolactone (PCL) 3D printed scaffolds onto BMP-2 adsorption efficacy and release.
|Journal series||Frontiers in Bioengineering and Biotechnology, ISSN , e-ISSN 2296-4185|
|Publication size in sheets||0.3|
|Conference||10th World Biomaterials Congress, 17-05-2016 - 22-05-2016, Montreal, Kanada|
|Keywords in English||biomaterial, growth factor, protein, 3D scaffold|
|Score|| = 0.0, 05-09-2019, ArticleFromJournal|
= 0.0, 05-09-2019, ArticleFromJournal
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