Manufacturing of substitutes for spongy bone with increased absorbability

Monika Budnicka , Agnieszka Gadomska-Gajadhur , Paweł Ruśkowski

Abstract

Composite scaffolds with increased hydrophilicity were prepared for the cancellous bone regeneration by the freeze-extraction method. As a construction material, a poly-L-lactide (plla) was applied. As a hydrophilic, modifying agent a methacrylic acid copolymer under trade name Eudragit® was used. A preliminary investigation and the optimization of the process were performed. For the obtained scaffolds, regression equations determining the effect: Eudragit® e100/plla weight ratio; volume ratio of methanol (porophore)/plla solution in dioxane on the interconnected porosity and the mass absorbability of obtained implants, were calculated.
Author Monika Budnicka (FC / CPCT)
Monika Budnicka,,
- Chair Of Polymer Chemistry And Technology
, Agnieszka Gadomska-Gajadhur (FC / CPCT)
Agnieszka Gadomska-Gajadhur,,
- Chair Of Polymer Chemistry And Technology
, Paweł Ruśkowski (FC / CPCT)
Paweł Ruśkowski,,
- Chair Of Polymer Chemistry And Technology
Pages65-79
Publication size in sheets0.7
Book EYEC Monograph: 8th European Young Engineers Conference, 2019, Politechnika Warszawska, Wydział Inżynierii Chemicznej i Procesowej, ISBN 978-83-936575-7-5, 364 p.
Keywords in Englishporous implant, polylactide, Eudragit®, freeze-extraction method.
URL https://www.eyec.ichip.pw.edu.pl/wp-content/uploads/Monograph-8th-EYEC.pdf
Languageen angielski
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wdpb_monografie_pliki_plik_monografia_164_org.pdf 517.44 KB
Score (nominal)0
Score sourceconferenceList
ScoreMinisterial score = 0.0, 24-06-2020, ChapterFromConference
Publication indicators WoS Citations = 1; GS Citations = 1.0
Citation count*1 (2020-06-23)
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