Production of 2-phenylethanol (PEA) by yeast with ionic liquids in situ extraction

Patrycja Okuniewska , Urszula Domańska-Żelazna , Aneta Pobudkowska-Mirecka , Jolanta Mierzejewska


PEA is a valuable aroma of a subtle rose scent used in food, perfume and household chemical industries, as well as a preservative (in medicines) and a disinfectant (e.g. for strawberries). High demand for PEA motivates the ongoing quest for new production methods. An alternative for synthetic PEA is obtaining this fragrance from rose petals. However, the costs of such production are very high – the price of rose oil (containing approx. 66–79% PEA [1]) is approx. 4,600 euro/kg [2]. The paper presents the application of yeasts for the PEA synthesis. The product of such synthesis, under the applicable law, is considered a natural product [3]. The only problem is the low final concentrations of the product. This can be solved using the in situ extraction [4]. There are the following methods for the PEA in situ extraction available: adsorption [5÷8], icrocapsules [9, 10], membrane extraction [11], liquid-liquid extraction using oleic acid [12, 13] or ILs [4, 9, 14÷17]. These methods allow for the increase of the production of PEA to approx. 6 g/L in case of flask cultures and 12 g/L to 26 g/L for fed-batch cultures [18]. The study focuses on the liquid-liquid extraction using ionic liquids due to the possibility to choose an ionic liquid for study purposes and the simplicity of this solution. The possibility to re-use the ionic liquid after the PEA re-extraction was another motive. The aim of the studies was to find the best ionic liquid for the extraction of PEA in situ.
Author Patrycja Okuniewska (FC / DPC)
Patrycja Okuniewska,,
- Department Of Physical Chemistry
, Urszula Domańska-Żelazna (FC / DPC)
Urszula Domańska-Żelazna,,
- Department Of Physical Chemistry
, Aneta Pobudkowska-Mirecka (FC / DPC)
Aneta Pobudkowska-Mirecka,,
- Department Of Physical Chemistry
, Jolanta Mierzejewska (FC / IBC / DDTB)
Jolanta Mierzejewska,,
- Department Of Drug Technology And Biotechnology
Journal seriesChemik: miesiecznik naukowo-techniczny, ISSN 0009-2886
Issue year2016
Publication size in sheets0.3
Keywords in EnglishPEA, 2-phenylethanol, yeast, ionic liquids, extraction
ASJC Classification1500 General Chemical Engineering; 1600 General Chemistry
Languageen angielski
wdpb_publikacje_pliki_plik_publikacja_2948_org.pdf 208.21 KB
Score (nominal)8
Score sourcejournalList
ScoreMinisterial score = 8.0, 17-08-2020, ArticleFromJournal
Ministerial score (2013-2016) = 8.0, 17-08-2020, ArticleFromJournal
Publication indicators WoS Citations = 2; Scopus Citations = 2; Scopus SNIP (Source Normalised Impact per Paper): 2016 = 0.292
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