Critical assessment of the quantitative criteria used in the comparison of nebulizers
Tomasz Robert Sosnowski
AbstractInhalation of aerosols from nebulizers remains an important method of drug delivery in treating diseases of the respiratory system. To be effective, aerosol droplets generated in nebulizers must hold certain size distribution which allow them to pass the oropharynx and be distributed in the bronchial tree. The assessment of droplet size distribution can be made by several experimental techniques and various quantitative parameters are used to characterize the operation of nebulizing devices. In this paper the physical meaning and usefulness of standard and non-standard quantitative parameters (i.e., MMAD, Dv50, FPF, GSD, Span) are discussed and followed by conclusions regarding their application to compare different nebulizers in the most reliable way
|Journal series||EC Pulmonology and Respiratory Medicine, (0 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||nebulizers, MMAD, Dv50, FPF, GSD, span|
|Score||= 5.0, 20-02-2020, ArticleFromJournal|
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