Poly-L-lactide scaffolds with super pores obtained by freeze-extraction method
Monika Budnicka , Dorota Kołbuk , Paweł Ruśkowski , Agnieszka Gadomska-Gajadhur
A nonplanar polylactide scaffold to be used in tissue engineering was obtained by freeze-extraction method. Properties of the scaffold were modified by adding Eudragit® E100. The impact of the modification on morphology, porosity and pore size, mass absorbability, mechanical properties was determined. Scanning electron microscopy (SEM), hydrostatic weighing test, static compression test was used to this end. The chemical composition of the scaffold was defined based on infrared spectroscopy (FTIR) and energy-dispersive X-ray spectroscopy (EDX). Biocompatibility was confirmed by quantitative tests and microscopic observation. The obtained results show that the obtained scaffolds may be applied as a carrier of hydrophilic cellular growth factors for more efficient tissue regeneration.
|Journal series||Journal of Biomedical Materials Research Part B-Applied Biomaterials, [Journal of Biomedical Materials Research - Part B Applied Biomaterials], ISSN 1552-4973, e-ISSN 1552-4981|
|Publication size in sheets||0.55|
|Score||= 140.0, 22-08-2020, ArticleFromJournal|
|Publication indicators||= 0; = 0; = 1.0; : 2018 = 0.915; : 2018 = 2.674 (2) - 2018=2.908 (5)|
|Citation count*||1 (2020-09-17)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.