Double casting prototyping with a thermal aging step for fabrication of 3D microstructures in poly(dimethylsiloxane)

Karina Kwapiszewska , Kamil Żukowski , Radosław Kwapiszewski , Zbigniew Brzózka


The paper describes a cheap and accessible technique of a poly(dimethylsiloxane) (PDMS) master treatment by thermal aging as a step of double casting microfabrication process. Three-dimensional PDMS microstructures could have been achieved using this technique. It was proved, that thermal aging changes nanotopology of a PDMS surface and thus enhances efficiency of double casting prototyping. The thermally aged PDMS master could have been used for multiple and correct replication of over 98% of the fabricated microstructures. Moreover, lack of chemical modification preserved the biocompatibility of PDMS devices. The fabricated microstructures were successfully utilized for 3D cell culture.
Author Karina Kwapiszewska - [Institute of Physical Chemistry of the Polish Academy of Sciences]
Karina Kwapiszewska ,,
, Kamil Żukowski (FC / IBC / DM)
Kamil Żukowski,,
- Department Of Microbioanalytics
, Radosław Kwapiszewski (FC / IBC / DM)
Radosław Kwapiszewski,,
- Department Of Microbioanalytics
, Zbigniew Brzózka (FC / IBC / DM)
Zbigniew Brzózka,,
- Department Of Microbioanalytics
Journal seriesAIMS Biophysics, ISSN 2377-9098
Issue year2016
Publication size in sheets0.5
Keywords in EnglishPDMS; microfabrication; 3D microstructures; biocompatible materials; double casting; thermal aging
ASJC Classification1312 Molecular Biology; 1303 Biochemistry; 1315 Structural Biology; 1304 Biophysics
Languageen angielski
Double casting prototyping with a thermal aging step for fabrication of.pdf 703.08 KB
Score (nominal)5
Score sourcejournalList
ScoreMinisterial score = 0.0, 12-12-2020, ArticleFromJournal
Ministerial score (2013-2016) = 5.0, 12-12-2020, ArticleFromJournal
Publication indicators WoS Citations = 3; Scopus Citations = 9; Scopus SNIP (Source Normalised Impact per Paper): 2016 = 0.314
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