Double casting prototyping with a thermal aging step for fabrication of 3D microstructures in poly(dimethylsiloxane)

Karina Kwapiszewska , Kamil Żukowski , Radosław Kwapiszewski , Zbigniew Brzózka

Abstract

The paper describes a cheap and accessible technique of a poly(dimethylsiloxane) (PDMS) master treatment by thermal aging as a step of double casting microfabrication process. Three-dimensional PDMS microstructures could have been achieved using this technique. It was proved, that thermal aging changes nanotopology of a PDMS surface and thus enhances efficiency of double casting prototyping. The thermally aged PDMS master could have been used for multiple and correct replication of over 98% of the fabricated microstructures. Moreover, lack of chemical modification preserved the biocompatibility of PDMS devices. The fabricated microstructures were successfully utilized for 3D cell culture.
Author Karina Kwapiszewska
Karina Kwapiszewska ,,
-
, Kamil Żukowski ZMB
Kamil Żukowski,,
- Department Of Microbioanalytics
, Radosław Kwapiszewski ZMB
Radosław Kwapiszewski,,
- Department Of Microbioanalytics
, Zbigniew Brzózka ZMB
Zbigniew Brzózka,,
- Department Of Microbioanalytics
Journal seriesAIMS Biophysics, ISSN 2377-9098
Issue year2016
Vol3
No4
Pages553-562
Publication size in sheets0.5
Keywords in EnglishPDMS; microfabrication; 3D microstructures; biocompatible materials; double casting; thermal aging
DOIDOI:10.3934/biophy.2016.4.553
URL http://www.aimspress.com/article/10.3934/biophy.2016.4.553
Languageen angielski
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Score (nominal)5
ScoreMinisterial score = 0.0, 28-11-2017, ArticleFromJournal
Ministerial score (2013-2016) = 5.0, 28-11-2017, ArticleFromJournal - czasopismo zagraniczne spoza list
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