Hydrogel coatings for artificial heart implants

Maciej Trzaskowski , Beata Aleksandra Butruk , Tomasz Ciach

Abstract

Polyurethanes (PU) are nowadays one of the most widely used types of polymers for biomedical applications. Th e segmented nature of these materials enables to obtain both fl exibility and mechanical strength within the same material. However, there is a need to modify a surface of PU in order to produce highly hemocompatible materials that can be used in fabrication of permanent blood-contacting devices such as vascular implants, valves or hearts. Among many types of modifi cations, hydrogel coating appears to be very promising. Such modifi cation increases the hydrophilicity of PU which in turn causes an increase in the bio- and hemocompatibility of the material. The aim of presented study was to create a polyvinylpyrrolidone (PVP) hydrogel coating onto a surface of polyurethane. A possibility of using a free radical polymerization reaction was investigated. Th e obtained materials were analyzed in terms of durability, swelling ratio and contact angle. Th e FTIR-ATR analysis confi rmed that polyurethane surfaces have been uccessfully coated with PVP.
Author Maciej Trzaskowski ZBIB
Maciej Trzaskowski ,,
- Department of Biotechnology and Bioprocess Engineering
, Beata Aleksandra Butruk ZBIB
Beata Aleksandra Butruk,,
- Department of Biotechnology and Bioprocess Engineering
, Tomasz Ciach ZBIB
Tomasz Ciach,,
- Department of Biotechnology and Bioprocess Engineering
Journal seriesChallenges of Modern Technology, ISSN 2082-2863, e-ISSN 2353-4419
Issue year2011
Vol2
No1
Pages19-22
Publication size in sheets0.5
Keywords in Englishpolyurethane, polyvinylpyrrolidone, hydrogel coating, artificial heart
URL http://nas.isep.pw.edu.pl/kok/journal/index.php/isuues/file/6-hydrogel-coatings-for-artifi-cial-heart-implants
Languageen angielski
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Citation count*4 (2018-07-20)
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