Effect of diesel-emitted nanostructured particles on the apparent surface rheology of model lung surfactant

Tomasz Robert Sosnowski , Agata Bożena Penconek , Katarzyna Jabłczyńska

Abstract

Diesel exhaust contain nanostructured particles which may be inhaled and may interact with the lung surfactant (LS) present in the respiratory system. This work reports the experimental analysis of surface tension variations in model LS system which contain diesel exhaust particles (DEPs). Experiments of oscillatory deformations of air/liquid interface under physiological-like conditions allowed to determine the changes in apparent surface rheological parameters, which indicated evident alteration of mechanical properties of LS caused by DEPs. These results allow to speculate on possible adverse effects of inhaled DEPs on LS in vivo. Work financed by National Science Centre (Poland) - project No. NCN 2014/13/B/ST8/00808.
Author Tomasz Robert Sosnowski KIPZ
Tomasz Robert Sosnowski,,
- Chair of Integrated Process Engineering
, Agata Bożena Penconek KIPZ
Agata Bożena Penconek,,
- Chair of Integrated Process Engineering
, Katarzyna Jabłczyńska KIPZ
Katarzyna Jabłczyńska,,
- Chair of Integrated Process Engineering
Pages446-448
Publication size in sheets0.3
Book 6th International Youth Science Forum “Litteris et Artibus”. Proceedings, 2016, Lviv Polytechnic Publishing House, ISBN 978-617-607-988-0, 508 p.LEA-2016_Proceedings.pdf (file archived - login or check accessibility on faculty)
Keywords in Englishnanostructured aerosol particles, diesel exhaust, lung surfactant, surface rheology, health effects
Languageen angielski
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Sosnowski T.R. (i in.) - Effect of diesel-emitted nanostructured....pdf (file archived - login or check accessibility on faculty) Sosnowski T.R. (i in.) - Effect of diesel-emitted nanostructured....pdf 1.43 MB
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