The influence of pH and concentration of mucins on diesel exhaust particles (DEPs) transport through artificial mucus

Agata Bożena Penconek , Arkadiusz Moskal

Abstract

Mucus layer is the first line of defense for the innate immune system. The mucus function is closely associated with its components and physicochemical and rheological properties. From the rheological point of view mucus is a highly non-Newtonian, thixotropic, viscoelastic material. The changes in mucus' composition, its properties as well as glycosylation process which develops with age and depends on environmental and health conditions lead to rheological changes. Due to the complexity of mucus' structure and possible defensemechanisms, it is very important to determine the effects of various factors, including various types of particles, drugs, microorganisms etc. on mucus' functions. In this study we focused on diesel exhaust particles (DEP) and their interaction with mucus. The results show that the transport of soot aggregates through mucus is affected not only by mucus' apparent viscosity. It is also possible that the interaction between the DEPs, their surface type, and the components of mucus strongly influence transport as well as the mucins’ concentration and the pH level.
Author Agata Bożena Penconek KIPZ
Agata Bożena Penconek,,
- Chair of Integrated Process Engineering
, Arkadiusz Moskal KIPZ
Arkadiusz Moskal,,
- Chair of Integrated Process Engineering
Journal seriesJournal of Aerosol Science, ISSN 0021-8502
Issue year2016
Vol102
Pages83-95
Publication size in sheets0.6
Keywords in Englishmucus, diesel exhaust particles, mucins, pH, barrier properties
DOIDOI:10.1016/j.jaerosci.2016.09.001
URL http://dx.doi.org/10.1016/j.jaerosci.2016.09.001
Languageen angielski
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Penconek A.B., Moskal A. - The influence of pH....pdf 1.53 MB
Score (nominal)35
ScoreMinisterial score [Punktacja MNiSW] = 35.0, 28-11-2017, ArticleFromJournal
Ministerial score (2013-2016) [Punktacja MNiSW (2013-2016)] = 35.0, 28-11-2017, ArticleFromJournal
Publication indicators WoS Impact Factor [Impact Factor WoS]: 2016 = 2.042 (2) - 2016=2.511 (5)
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