Polyurethane modification with acrylic acid by Ce(IV)-initiated graft polymerization
Beata Aleksandra Butruk-Raszeja , Paulina Anna Trzaskowska , Aleksandra Kuźmińska , Tomasz Ciach
AbstractThis paper presents a method for polyurethane surface functionalization for tissue engineering applications. Functionalization has been carried out by grafting acrylic acid to the polyurethane surface with the use of radical polymerization with a Ce4+ initiator. Contrary to other papers suggesting that the presence of hydroxyl groups are essential for successful grafting via ceric ions, we propose a method with the omission of the surface hydroxylation step. The influence of reaction conditions: reaction time, reaction temperature and monomer concentration on carboxyl groups surface density has been analyzed and described. The quantity of carboxyl groups on the surface was determined with the use of the TBO method. Materials grafted with acrylic acid have been subjected to conjugation with a peptide using sulfoNHS/ EDC chemistry. Successful incorporation of the peptide has been confirmed by an ELISA assay. Additionally, for better characterization, after each step of modification materials were subjected to SEM, FTIR-ATR, XPS and contact angle measurement analysis.
|Journal series||Open Chemistry, ISSN , e-ISSN 2391-5420|
|Publication size in sheets||0.5|
|Keywords in English||polyurethane, surface modification, acrylic acid, peptide coating, cerium-induced grafting|
|Score|| = 14.0, 11-05-2020, ArticleFromJournal|
= 14.0, 11-05-2020, ArticleFromJournal
|Publication indicators||= 4; = 4; = 5.0; : 2016 = 0.587; : 2016 = 1.027 (2) - 2016=1.048 (5)|
|Citation count*||5 (2020-09-23)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.