Magnetic Resonance quantification of myocardial perfusion reserve using Fermi function model: comparison to visual qualification

Tomasz Kubik , Konrad Werys , Krzysztof Mikołajczyk , Śpiewak Mateusz , Petryka-Mazurkiewicz Joanna , Miśko Jolanta


Quantitative perfusion assessment using magnetic resonance imaging (MRI) is one of the methods used in Coronary Artery Disease (CAD) diagnosis. In this study we investigated the possibility of performing perfusion quantification using Fermi function modeling on the data acquired in the way typical for visual perfusion assessment with high dose of contrast agent. 25 patients with CAD symptoms have been examined by MRI in stress and rest condition. Image processing and numerical model have been implemented to quantify myocardial perfusion reserve (MPR). The results have been compared with the visual perfusion reserve qualification by an experienced physician. Accuracy of quantitative method in classification perfusion in myocardial segments was below 80 %, meaning this method in this setup is not yet ready for clinical applications.
Author Tomasz Kubik IMIB
Tomasz Kubik,,
- The Institute of Metrology and Biomedical Engineering
, Konrad Werys IRTM
Konrad Werys,,
- The Institute of Radioelectronics and Multimedia Technology
, Krzysztof Mikołajczyk IMIB
Krzysztof Mikołajczyk,,
- The Institute of Metrology and Biomedical Engineering
, Śpiewak Mateusz
Śpiewak Mateusz,,
, Petryka-Mazurkiewicz Joanna
Petryka-Mazurkiewicz Joanna,,
, Miśko Jolanta
Miśko Jolanta,,
Publication size in sheets0.5
Book Jabłoński Ryszard, Brezina Tomas (eds.): Advanced Mechatronics Solutions, Advances in Intelligent Systems and Computing, 2016, Springer, ISBN 978-3-319-23921-7, 668 p., DOI:10.1007/978-3-319-23923-1
Keywords in EnglishCardiac Magnetic Resonance Myocardial Perfusion Reserve Fermi deconvolution Coronary Artery Disease
Languageen angielski
Score (nominal)15
ScoreMinisterial score = 15.0, 27-03-2017, BookChapterSeriesAndMatConfByIndicator
Ministerial score (2013-2016) = 15.0, 27-03-2017, BookChapterSeriesAndMatConfByIndicator
Citation count*0 (2016-06-05)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.