Interactions of insoluble micro- and nanoparticles with the air-liquid interface of the model pulmonary fluids

Katarzyna Ewa Dobrowolska , Katarzyna Jabłczyńska , Dorota Kondej , Tomasz Robert Sosnowski


The work discusses physicochemical phenomena related to interactions between the inhaled particles and the surface of pulmonary fluid which contains the lung surfactant. Dynamic surface phenomena which arise due to periodical variations of the interfacial area during breathing cycle are the extraordinary feature of this system and they are strictly related to the mechanics of ventilation and the pulmonary mass transfer processes. Presence of foreign material such as inhaled micro - and nanoparticles with dif ferent size, surface properties and morphology may alter these phenomena which may have some health consequences. This effect is discussed on two examples: mineral particles (CeO 2 ) and carbonaceous particles emitted from diesel engine running on two differ ent fuels. Two experimental methods of research in this field are presented: the Langmuir balance and the oscillating pendant drop. The results show the sensitivity of dynamic surface properties of the lung surfactant on exogenous materials which may be in troduced to the respiratory system by inhalation of dusty air. Some physicochemical interpretation of these results is presented.
Author Katarzyna Ewa Dobrowolska KIPZ
Katarzyna Ewa Dobrowolska,,
- Chair of Integrated Process Engineering
, Katarzyna Jabłczyńska KIPZ
Katarzyna Jabłczyńska,,
- Chair of Integrated Process Engineering
, Dorota Kondej - Central Institute for Labour Protection - National Research Institute (CIOP PIB)
Dorota Kondej,,
, Tomasz Robert Sosnowski KIPZ
Tomasz Robert Sosnowski,,
- Chair of Integrated Process Engineering
Journal seriesPhysicochemical Problems of Mineral Processing, ISSN 1643-1049 [0137-1282]
Issue year2018
Keywords in Englishlung surfactant, pulmonary fluids, air - liquid interface, compressibility, nanoparticle
Languageen angielski
Dobrowolska K. (i in.) - Interactions of insoluble....pdf 1.03 MB
Score (nominal)25
ScoreMinisterial score = 20.0, 27-10-2017, ArticleFromJournal
Ministerial score (2013-2016) = 25.0, 27-10-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2016 = 0.901 (2) - 2016=1.013 (5)
Citation count*0 (2018-07-18)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.