Alginate – current use and future perspectives in pharmaceutical and biomedical applications

Marta Szekalska , Agata Puciłowska , Emilia Szymańska , Patrycja Ciosek , Katarzyna Winnicka

Abstract

Over the last decades, alginates, naturalmultifunctional polymers, have increasingly drawn attention as attractive compounds in the biomedical and pharmaceutical fields due to their unique physicochemical properties and versatile biological activities.The focus of the paper is to describe biological and pharmacological activity of alginates and to discuss the present use and future possibilities of alginates as a tool in drug formulation. The recent technological advancements with using alginates, issues related to alginates suitability as matrix for three-dimensional tissue cultures, adjuvants of antibiotics, and antiviral agents in cell transplantation in diabetes or neurodegenerative diseases treatment, and an update on the antimicrobial and antiviral therapy of the alginate based drugs are also highlighted.
Author Marta Szekalska
Marta Szekalska,,
-
, Agata Puciłowska
Agata Puciłowska,,
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, Emilia Szymańska
Emilia Szymańska,,
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, Patrycja Ciosek ZMB
Patrycja Ciosek,,
- Department Of Microbioanalytics
, Katarzyna Winnicka
Katarzyna Winnicka,,
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Journal seriesInternational Journal of Polymer Science, ISSN 1687-9422
Issue year2016
Vol2016
Pages1-17
Publication size in sheets0.8
DOIDOI:10.1155/2016/7697031
URL https://www.hindawi.com/journals/ijps/2016/7697031/
Languageen angielski
File
Ciosek.pdf 2.28 MB
Score (nominal)25
ScoreMinisterial score [Punktacja MNiSW] = 25.0, 28-11-2017, ArticleFromJournal
Ministerial score (2013-2016) [Punktacja MNiSW (2013-2016)] = 25.0, 28-11-2017, ArticleFromJournal
Publication indicators WoS Impact Factor [Impact Factor WoS]: 2016 = 1.077 (2) - 2016=1.837 (5)
Citation count*0
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