Continuous Multimodality Monitoring in Children after Traumatic Brain Injury—Preliminary Experience

Adam M. H. Young , Joseph Donnelly , Marek Czosnyka , Ibrahim Jalloh , X. Liu , M.J.H. Aries , Helen M. Fernandes , Matthew R. Garnett , Peter Smielewski , P. J Hutchinson , Shruti Agrawal


Multimodality monitoring is regularly employed in adult traumatic brain injury (TBI) patients where it provides physiologic and therapeutic insight into this heterogeneous condition. Pediatric studies are less frequent. METHODS: An analysis of data collected prospectively from 12 pediatric TBI patients admitted to Addenbrooke's Hospital, Pediatric Intensive Care Unit (PICU) between August 2012 and December 2014 was performed. Patients' intracranial pressure (ICP), mean arterial pressure (MAP), and cerebral perfusion pressure (CPP) were monitored continuously using brain monitoring software ICM+®,) Pressure reactivity index (PRx) and 'Optimal CPP' (CPPopt) were calculated. Patient outcome was dichotomized into survivors and non-survivors
Author Adam M. H. Young - [University of Cambridge]
Adam M. H. Young,,
, Joseph Donnelly - [University of Cambridge]
Joseph Donnelly,,
, Marek Czosnyka (FEIT / PE)
Marek Czosnyka,,
- The Institute of Electronic Systems
, Ibrahim Jalloh - [University of Cambridge]
Ibrahim Jalloh,,
, X. Liu - [University of Cambridge]
X. Liu,,
, M.J.H. Aries - [University of Cambridge]
M.J.H. Aries,,
, Helen M. Fernandes - [University of Cambridge]
Helen M. Fernandes,,
, Matthew R. Garnett - [University of Cambridge]
Matthew R. Garnett,,
, Peter Smielewski - [University of Cambridge]
Peter Smielewski,,
, P. J Hutchinson - [University of Cambridge]
P. J Hutchinson,,
et al.`
Journal seriesPlos One, ISSN 1932-6203
Issue year2016
Publication size in sheets0.5
ASJC Classification1100 General Agricultural and Biological Sciences; 1300 General Biochemistry, Genetics and Molecular Biology; 2700 General Medicine
Languageen angielski
Score (nominal)40
Score sourcejournalList
ScoreMinisterial score = 35.0, 30-01-2020, ArticleFromJournal
Ministerial score (2013-2016) = 40.0, 30-01-2020, ArticleFromJournal
Publication indicators Scopus Citations = 20; WoS Citations = 16; Scopus SNIP (Source Normalised Impact per Paper): 2016 = 1.101; WoS Impact Factor: 2016 = 2.806 (2) - 2016=3.394 (5)
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