Electrospun poly(L-lactic)acid/nanoalumina (PLA/Al2O3) composite fiber mats with potential biomedical application - investigation of cytotoxicity

Patrycja Kurtycz , Tomasz Ciach , Andrzej Olszyna , Antoni Kunicki , E. Radziun , M. Rosłon , J. Dudkiewicz-Wilczyńska , K. Nowak , E. Anuszewska


PLA fibrous mats containing nanoalumina filler were fabricated by electrospinning method. The morphology of the mats was characterized by SEM, and TEM. In vitro biocompatibility of the electrospun fiber mats was also evaluated. Indirect cytotoxicity evaluation of the fiber mats with human skin fibroblasts revealed that the materials were non-toxic to living cells. The cells cultured on the fibrous mat exhibited normal cells shapes and were integrated well with surrounding fibers. The obtained results confirmed the potential for use of the electrosupun PLA/Al2O3 fiber mats for biomedical application.
Author Patrycja Kurtycz (FMSE)
Patrycja Kurtycz,,
- Faculty of Materials Science and Engineering
, Tomasz Ciach (FCPE / DBBE)
Tomasz Ciach,,
- Department of Biotechnology and Bioprocess Engineering
, Andrzej Olszyna (FMSE / DSMP)
Andrzej Olszyna,,
- Division of Ceramic Materials and Polymers
, Antoni Kunicki (FC / DCOC)
Antoni Kunicki,,
- Department Of Catalysis And Organometallic Chemistry
, E. Radziun - [Warsaw University of Technology (PW)]
E. Radziun,,
- Politechnika Warszawska
, M. Rosłon - [Politechnika Warszawska]
M. Rosłon,,
, J. Dudkiewicz-Wilczyńska - [Politechnika Warszawska]
J. Dudkiewicz-Wilczyńska,,
, K. Nowak - [Politechnika Warszawska]
K. Nowak,,
, E. Anuszewska - [Politechnika Warszawska]
E. Anuszewska,,
Journal seriesFibers and Polymers, ISSN 1229-9197
Issue year2013
Publication size in sheets0.5
Keywords in EnglishPLA, alumina, electrospinning, cytotoxicity, fiber mats
ASJC Classification2507 Polymers and Plastics; 1500 General Chemical Engineering; 1600 General Chemistry
URL http://link.springer.com/article/10.1007%2Fs12221-013-0578-5
Languageen angielski
Kurtycz P. (i in.) - Electrospun poly(L-lactic)acid-nanoalumina (PLA-Al2O3)....pdf 992.92 KB
Score (nominal)30
Score sourcejournalList
ScoreMinisterial score = 25.0, 06-04-2020, ArticleFromJournal
Ministerial score (2013-2016) = 30.0, 06-04-2020, ArticleFromJournal
Publication indicators Scopus Citations = 8; WoS Citations = 8; GS Citations = 11.0; Scopus SNIP (Source Normalised Impact per Paper): 2013 = 1.038; WoS Impact Factor: 2013 = 1.113 (2) - 2013=1.361 (5)
Citation count*12 (2020-08-27)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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