Effect of hydroxyapatite nanoparticles addition on structure properties of poly(L-lactide-co-glycolide) After gamma sterilization

Olga Urbanek , F. Pierini , Emilia Choińska , P. Sajkiewicz , Monika Bil , Wojciech Święszkowski


Physical and chemical factors resulting from the sterilization methods may affect the structure and properties of the materials which undergo this procedure. Poly(l-lactide-co-glicolide) (PLGA) is commonly used for medical applications, but, due to its inadequate mechanical properties, it is not recommended for load-bearing applications. One of the methods for improving PLGA mechanical properties is addition of hydroxyapatite nanoparticles (nHAp). The aim of this study was to evaluate the effect of nanoparticles addition on PLGA structure and properties after gamma radiation. According to our results, reduction of the molecular mass caused by gamma radiation was lower for PLGA with nHAp addition. Differential scanning calorimetry (DSC) analysis indicates an increase of crystallinity caused both by nHAp and gamma radiation. The first phenomenon can be explained by heteronucleation, while the second one is most probably related to higher molecular mobility of degrading polymer. Moreover, addition of nanoparticles increases thermal stability and affects the Young's modulus changes after gamma radiation.
Author Olga Urbanek
Olga Urbanek,,
, F. Pierini
F. Pierini,,
, Emilia Choińska ZPM
Emilia Choińska,,
- Division of Materials Design
, P. Sajkiewicz
P. Sajkiewicz,,
, Monika Bil ZPM
Monika Bil,,
- Division of Materials Design
, Wojciech Święszkowski ZPM
Wojciech Święszkowski,,
- Division of Materials Design
Journal seriesPolymer Composites, ISSN 0272-8397
Issue year2016
Publication size in sheets0.5
URL http://onlinelibrary.wiley.com/doi/10.1002/pc.24028/full
Languageen angielski
Urbanek_et_al-2016-Polymer_Composites.pdf 530.68 KB
Score (nominal)30
ScoreMinisterial score = 30.0, 28-11-2017, ArticleFromJournal
Ministerial score (2013-2016) = 30.0, 28-11-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2016 = 2.324 (2) - 2016=2.121 (5)
Citation count*3 (2018-05-25)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.