Synthesis of unsymmetrical alkyl acetals via addition of primary alcohols to allyl ethers mediated by ruthenium complexes
S. Krompiec , Mateusz Penkala , E Kowalska , Robert Penczek , Piotr Bujak , Witold Danikiewicz , Grzegorz Spólnik , Andrzej Kita , Iwona Grudzka
Ru-catalyzed synthesis of mixed alkyl-alkyl acetals via addition of primary alcohols to allyl ethers has been extended to include long-chain and/or functionalized substrates. The catalytic systems for these reactions were generated from RuCl 2(PPh 3) 3 and [RuCl 2(1,5-COD)] x and phosphines [PPh 3 or P(p-chlorophenyl) 3] or SbPh 3. Of particular importance is the almost quantitative elimination of transacetalization. The addition proceeds through allyl complexes, not via isomerization of allyl ethers - subsequent addition of ROH to vinyl ethers. © The Author(s) 2011.
|Journal series||Monatshefte für Chemie, ISSN 0026-9247, e-ISSN 1434-4475, (A 25 pkt)|
|Publication indicators||= 4; = 4; : 2011 = 0.756; : 2011 = 1.532 (2) - 2011=1.543 (5)|
|Citation count*||5 (2015-04-20)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.