Straightforward synthesis and crystal structures of the 3-piperazine-bisbenzoxaboroles and their boronic acid analogs
Agnieszka Adamczyk-Woźniak , Krzysztof M. Borys , Izabela D. Madura , Stanisław Michałek , Alicja Pawełko
AbstractThe straightforward synthesis of a highly biologically active 3-piperazine-bisbenzoxaborole and its fluorine analog has been described. The obtained bisbenzoxaboroles have been used in the synthesis of their phenylboronic acids analogs. One diboronic acid has been also isolated as hydrochloride salt as well as its methyl monoester. All the described compounds display unique molecular architectures, which have been determined by X-ray measurements.
|Journal series||Tetrahedron, ISSN 0040-4020|
|Publication size in sheets||0.5|
|Keywords in English||benzoxaborole, diboronic, bisboronic, monoester, piperazine, boronic acid|
|ASJC Classification||; ;|
|Score|| = 30.0, 15-11-2019, ArticleFromJournal|
= 30.0, 15-11-2019, ArticleFromJournal
|Publication indicators||= 17; = 15; : 2014 = 0.905; : 2013 = 2.817 (2) - 2013=2.772 (5)|
|Citation count*||7 (2016-06-01)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.