The DNA Assembler for Next Generation Sequencers

Jan Twardowski , Robert Marek Nowak

Abstract

The aim of this paper is new application for de novo assembly DNA reads produced by next generation sequencers. The algorithm based on de Bruin graph is proposed, it uses both DNA strands: coding and complementary. The read errors are corrected. The repetitive sequences longer than read are correctly reconstructed in some cases. The application in client-server architecture was developed and tested on pseudo-random sequences and reads generated from genomes of model organisms. © (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Author Jan Twardowski
Jan Twardowski,,
-
, Robert Marek Nowak (FEIT / PE)
Robert Marek Nowak,,
- The Institute of Electronic Systems
Pages890317-1-890317-6
Book Romaniuk Ryszard (eds.): Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2013, vol. 8903, 2013, SPIE P.O. Box 10, Bellingham, Washington 98227-0010 USA , SPIE, ISBN 9780819497857, [ISSN 0277-786X ], 410 p., DOI:10.1117/12.2049644
DOIDOI:10.1117/12.2032637
Languageen angielski
Score (nominal)15
Score sourceconferenceIndex
ScoreMinisterial score = 10.0, 29-08-2020, BookChapterMatConfByIndicator
Ministerial score (2013-2016) = 15.0, 29-08-2020, BookChapterMatConfByIndicator
Publication indicators WoS Citations = 1; Scopus Citations = 1
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