The DNA Assembler for Next Generation Sequencers
- Jan Twardowski,
- Robert Marek Nowak
The aim of this paper is new application for de novo assembly DNA reads produced by next generation sequencers. The algorithm based on de Bruin graph is proposed, it uses both DNA strands: coding and complementary. The read errors are corrected. The repetitive sequences longer than read are correctly reconstructed in some cases. The application in client-server architecture was developed and tested on pseudo-random sequences and reads generated from genomes of model organisms. © (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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- Romaniuk Ryszard Ryszard Romaniuk (eds.): Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2013, vol. 8903, 2013, SPIE P.O. Box 10, Bellingham, Washington 98227-0010 USA , SPIE, 410 p., ISBN 9780819497857. DOI:10.1117/12.2049644 Opening in a new tab
- DOI:10.1117/12.2032637 Opening in a new tab
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