Discrimination of the Micro Electrode Recordings for STN Localization during DBS Surgery in Parkinson’s Patients

Konrad Andrzej Ciecierski , Zbigniew W. Raś , Andrzej W. Przybyszewski

Abstract

During deep brain stimulation (DBS) treatment of Parkinson disease, the target of the surgery is a small (9 x 7 x 4 mm) deep within brain placed structure called Subthalamic Nucleus (STN). It is similar morphologically to the surrounding tissue and as such poorly visible in CT or MRI. The goal of the surgery is the permanent precise placement of the stimulating electrode within target nucleus. Precision is extremely important as wrong placement of the stimulating electrode may lead to serious mood disturbances. To obtain exact location of the STN nucleus an intraoperative stereotactic supportive navigation is being used. A set of 3 to 5 parallel micro electrodes is inserted into brain and in measured steps advanced towards expected location of the nucleus. At each step electrodes record activity of the surrounding neural tissue. Because STN has a distinct physiology, the signals recorded within it also display specific features. It is therefore possible to provide analytical methods targeted for detection of those STN specific characteristics. Basing on such methods this paper presents clustering and classification approaches for discrimination of the micro electrode recordings coming from the STN nucleus. Application of those methods during the neurosurgical procedure might lessen the risks of medical complications and might also shorten the – out of necessity awake – part of the surgery.
Author Konrad Andrzej Ciecierski (FEIT / IN)
Konrad Andrzej Ciecierski,,
- The Institute of Computer Science
, Zbigniew W. Raś (FEIT / IN)
Zbigniew W. Raś,,
- The Institute of Computer Science
, Andrzej W. Przybyszewski
Andrzej W. Przybyszewski,,
-
Pages328-339
Book Larsen Henrik Legind , Martin-Bautista Maria J. , Vila María Amparo , Andreasen Troels , Christiansen Henning (eds.): Flexible Query Answering Systems. 10th International Conference, FQAS 2013, Proceedings, Lecture Notes In Computer Science, vol. 8132, 2013, Heidelberg New York Dordrecht London, Springer Berlin Heidelberg, ISBN 978-3-642-40768-0, [978-3-642-40769-7], 693 p., DOI:10.1007/978-3-642-40769-7
front-matter1.pdf / 194.45 KB / No licence information
DOIDOI:10.1007/978-3-642-40769-7_29
URL http://link.springer.com/chapter/10.1007%2F978-3-642-40769-7_29
ProjectDevelopment of new methods and algorithms in the following areas: computer graphics, artificial intelligence, and information systems, and distributed systems . Project leader: Rybiński Henryk, , Phone: +48 22 234 7731, start date 29-05-2012, planned end date 31-12-2012, end date 30-11-2013, II/2012/DS/1, Completed
WEiTI Działalność statutowa
Languageen angielski
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paper01.pdf 1,005.62 KB
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upoważnienie_01-signed-3.pdf 127.68 KB
Score (nominal)0
Score sourcejournalList
ScoreMinisterial score = 0.0, 01-02-2020, BookChapterSeriesAndMatConfByIndicator
Ministerial score (2013-2016) = 0.0, 01-02-2020, BookChapterSeriesAndMatConfByIndicator
Citation count*8 (2020-09-16)
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