Brush Swelling and Attachment Strength of Barnacle Adhesion Protein on Zwitterionic Polymer Films as a Function of Macromolecular Structure

Shifeng Guo , R. Quintana , Marco Cirelli , Zi Siang Desmond Toa , Vivek Arjunan Vasantha , E. Stefan Kooij , Dominik Jańczewski , G. J. Vancso

Abstract

The exceptional hydration of sulfobetaine polymer brushes and their resistance toward nonspecific protein absorption allows for the construction of thin films with excellent antibiofouling properties. In this work, swollen sulfobetaine brushes, prepared by surface-initiated atom transfer radical polymerization of two monomers, differentiated by the nature of the polymerizable group, are studied and compared by a liquid-cell atomic force microscopy technique and spectroscopic ellipsometry. Colloidal AFM-based force spectroscopy is employed to estimate brush grafting density and characterize nanomechanical properties in salt water. When the ionic strength-induced swelling behaviors of the two systems are compared, the differences observed on the antipolyelectrolyte response can be correlated with the stiffness variation on brush compression, likely to be promoted by solvation differences. The higher solvation of amide groups is proposed to be responsible for the lower adhesion force of the barnacle cyprid’s temporary adhesive proteins. The adhesion results provide further insights into the antibiofouling activity against barnacle cyprid settlement attributed to polysulfobetaine brushes.
Author Shifeng Guo
Shifeng Guo,,
-
, R. Quintana
R. Quintana,,
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, Marco Cirelli
Marco Cirelli,,
-
, Zi Siang Desmond Toa
Zi Siang Desmond Toa,,
-
, Vivek Arjunan Vasantha
Vivek Arjunan Vasantha,,
-
, E. Stefan Kooij
E. Stefan Kooij,,
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, Dominik Jańczewski (FC / CPCT)
Dominik Jańczewski,,
- Chair Of Polymer Chemistry And Technology
, G. J. Vancso
G. J. Vancso,,
-
Journal seriesLangmuir, ISSN 0743-7463, (A 35 pkt)
Issue year2019
Vol35
No24
Pages8085-8094
Publication size in sheets0.5
ASJC Classification1603 Electrochemistry; 1607 Spectroscopy; 3110 Surfaces and Interfaces; 3104 Condensed Matter Physics; 2500 General Materials Science
DOIDOI:10.1021/acs.langmuir.9b00918
Languageen angielski
File
wdpb_publikacje_pliki_plik_publikacja_3696_org.pdf 2.21 MB
Score (nominal)35
ScoreMinisterial score = 35.0, 24-07-2019, ArticleFromJournal
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2016 = 1.188; WoS Impact Factor: 2017 = 3.789 (2) - 2017=4.139 (5)
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