The influence of chemical polishing of titanium scaffolds on their mechanical strength and in-vitro cell response

Bartłomiej Wysocki , Joanna Idaszek , Joseph Buhagiar , Karol Szlązak , Tomasz Brynk , Krzysztof Kurzydłowski , Wojciech Święszkowski

Abstract

Selective Laser Melting (SLM) is a powder-bed-based additive manufacturing method, using a laser beam, which can be used to produce metallic scaffolds for bone regeneration. However, this process also has a few disadvantages. One of its drawbacks is the necessity of post-processing in order to improve the surface finish. Another drawback lies in the removal of unmelted powder particles from the build. In this study, the influence of chemical polishing of SLM fabricated titanium scaffolds on their mechanical strength and in vitro cellular response was investigated. Scaffolds with bimodal pore size (200 µm core and 500 µm shell) were fabricated by SLM from commercially pure titanium powder and then chemically treated in HF/HNO3 solutions to remove unmelted powder particles. The cell viability and mechanical strength were compared between as-made and chemically-treated scaffolds. The chemical treatment was successful in the removal of unmelted powder particles from the titanium scaffold. The Young’s modulus of the fabricated cellular structures was of 42.7 and 13.3 GPa for as-made and chemically-treated scaffolds respectively. These values are very similar to the Young’s modulus of living human bone. Chemical treatment did not affect negatively cell proliferation and differentiation. Additionally, the chemically-treated scaffolds had a twofold increase in colonization of osteoblast cells migrating out of multicellular spheroids. Furthermore, X-ray computed microtomography confirmed that chemically-treated scaffolds met the dimensions originally set in the CAD models. Therefore, chemical-treatment can be used as a tool to cancel the discrepancies between the designed and fabricated objects, thus enabling fabrication of finer structures with regular struts and high resolution.
Author Bartłomiej Wysocki (FMSE / DMD)
Bartłomiej Wysocki,,
- Division of Materials Design
, Joanna Idaszek (FMSE / DMD)
Joanna Idaszek,,
- Division of Materials Design
, Joseph Buhagiar - University of Malta [University of Malta]
Joseph Buhagiar,,
-
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, Karol Szlązak (FMSE / DMD)
Karol Szlązak,,
- Division of Materials Design
, Tomasz Brynk (FMSE / DMD)
Tomasz Brynk,,
- Division of Materials Design
, Krzysztof Kurzydłowski (FMSE / DMD)
Krzysztof Kurzydłowski,,
- Division of Materials Design
, Wojciech Święszkowski (FMSE / DMD)
Wojciech Święszkowski,,
- Division of Materials Design
Journal seriesMaterials Science & Engineering C - Materials for Biological Applications, ISSN 0928-4931, (A 30 pkt)
Issue year2019
Vol95
Pages428-439
Publication size in sheets0.55
Keywords in EnglishSelective laser melting; CP Ti; Titanium scaffolds; Mechanical properties; Chemical treatments; Cell behaviour
ASJC Classification2210 Mechanical Engineering; 2211 Mechanics of Materials; 3104 Condensed Matter Physics; 2500 General Materials Science
DOIDOI:10.1016/j.msec.2018.04.019
Languageen angielski
File
10.1016j.msec.2018.04.019.pdf 2.27 MB
Score (nominal)30
ScoreMinisterial score = 30.0, 17-01-2019, ArticleFromJournal
Ministerial score (2013-2016) = 30.0, 17-01-2019, ArticleFromJournal
Publication indicators Scopus SNIP (Source Normalised Impact per Paper): 2017 = 1.384; WoS Impact Factor: 2017 = 5.08 (2) - 2017=4.628 (5); Scopus Citations = 0; WoS Citations = 1
Citation count*2 (2019-08-22)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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