Lipase-Catalyzed Kinetic Resolution of the Racemic Mixtures of 1-Aryloxy-3-Nitrato-and 1-Aryloxy-3-Azido-2-Propanols

Beata Pchelka , Justyna Radomska , Jan Plenkiewicz

Abstract

Abstract The racemic mixtures of 1-aryloxy-3-nitrato-2-propanols and 1-aryloxy-3-azido-2-propanols were resolved with moderate selectivity by the lipase-mediated acylation with vinyl acetate. The effects of the nature, position, and spatial requirements of the phenyl-ring substituents on the resolution degree were investigated.
Author Beata Pchelka
Beata Pchelka,,
-
, Justyna Radomska
Justyna Radomska,,
-
, Jan Plenkiewicz WCh
Jan Plenkiewicz,,
- Faculty of Chemistry
Journal seriesSynthetic Communications, ISSN 0039-7911
Issue year1998
Vol28
No23
Pages4355-4364
DOIDOI:10.1080/00397919808004470
URL http://www.tandfonline.com/doi/abs/10.1080/00397919808004470
Languageen angielski
Score (nominal)20
Publication indicators WoS Impact Factor: 2006 = 1.001 (2) - 2007=1.008 (5)
Citation count*6 (2013-01-30)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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