Enzymatic and Microbial Method of Preparation of Optically Active (±) 3-Methyl-4-phenyl-4,5-dihydroisoxazole-4-carboxylic Acid
Irmina Zadrożna , J. Kurkowska , I. Makuch
AbstractAbstract: A racemic mixture of ethyl-3-methyl-4-phenyl-4,5-dihydroisoxasole-4-carboxylate was obtained in the 1,3-dipolar intermolecular cycloaddition of ethyl atroponate and aliphatic nitrile oxide, which was then subjected to enzymatic and microbiological hydrolysis in order to obtain optically active acids. Warsaw University of Technology, Faculty of Chemistry ul. Noakowskiego 3, PL-00-664 Warsaw, Poland
|Journal series||Synthetic Communications, ISSN 0039-7911|
|Publication indicators||: 2006 = 1.001 (2) - 2007=1.008 (5)|
|Citation count*||7 (2013-01-30)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.