Enzymatic and Microbial Method of Preparation of Optically Active (±) 3-Methyl-4-phenyl-4,5-dihydroisoxazole-4-carboxylic Acid

Irmina Zadrożna , J. Kurkowska , I. Makuch

Abstract

Abstract: A racemic mixture of ethyl-3-methyl-4-phenyl-4,5-dihydroisoxasole-4-carboxylate was obtained in the 1,3-dipolar intermolecular cycloaddition of ethyl atroponate and aliphatic nitrile oxide, which was then subjected to enzymatic and microbiological hydrolysis in order to obtain optically active acids. Warsaw University of Technology, Faculty of Chemistry ul. Noakowskiego 3, PL-00-664 Warsaw, Poland
Author Irmina Zadrożna (FC)
Irmina Zadrożna,,
- Faculty of Chemistry
, J. Kurkowska
J. Kurkowska,,
-
, I. Makuch
I. Makuch,,
-
Journal seriesSynthetic Communications, ISSN 0039-7911
Issue year1997
Vol27
No23
Pages4181-4191
DOIDOI:10.1080/00397919708005466
URL http://www.tandfonline.com/doi/abs/10.1080/00397919708005466
Score (nominal)20
Publication indicators WoS Impact Factor: 2006 = 1.001 (2) - 2007=1.008 (5)
Citation count*7 (2013-01-30)
Cite
Share Share

Get link to the record


* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
Back
Confirmation
Are you sure?