Polymorphism of (+)N-tosyl-L-glutamic acid
Halina Hajmowicz , Ludwik Synoradzki , Krzysztof Bujnowski , Janusz Zachara
AbstractIt has been shown that polymorphism is the reason for the occurrence of (+)N-tosyl-L-glutamic acid 1 with various melting points. 1 occurs in two crystalline forms: α and β. Form α-1 (prisms) having a melting point of 145–147°C is chemically pure and stable. Form β-1, however, is unstable and is formed as a result of the stabilizing effect of an organic solvent not introduced into the structure of the crystal. At about 125°C the β forms is transformed to the α form. The melting point of the β form depends on the amount and type of solvent contained in the crystal, which, during measurement cannot leave the system.
|Journal series||Journal of thermal analysis, ISSN 0022-5215, 1572-8943|
|Keywords in English||Crystallization, Inorganic Chemistry, Measurement Science, Instrumentation, melting point, N-tosyl-L-glutamic acid, Physical Chemistry, Polymer Sciences, Polymorphism, thermogravimetric analysis, X-ray powder diffraction|
|Abstract in Polish||xxx|
|Publication indicators||= 2; = 1.0|
|Citation count*||1 (2015-04-26)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.