A role of network arrangements of microcirculation vessels in cardiovascular function

Krzysztof Cieślicki , Jerzy Przybylski

Abstract

The objective of the work was to explain the mechanisms for the appearance or creation of the so-called preferential channels for blood flow in tissues. We postulated that the addressed preferential blood flow occurs at the level of network structure of vascular system and results directly from its heterogeneity. The studies have been done in regular, two-dimensional network model of microvessels. Due to poorly defined dimensions, shapes and tortuousity of real vessels, the values of network elements were random. We examined how the heterogeneity of network elements influences flow redistribution within the network and the global network resistance to flow. The results indicated that the higher segmental resistance scatters the greater probability of the appearance within the network preferential flow paths passing through the whole network or being its local singularity. These channels significantly reduce the effect the global network resistance increases.
Author Krzysztof Cieślicki (FM / IACR)
Krzysztof Cieślicki,,
- The Institute of Automatic Control and Robotics
, Jerzy Przybylski (FoEE / ICIE)
Jerzy Przybylski,,
- The Institute of Control and Industrial Electronics
Journal seriesMedical Hypotheses, ISSN 0306-9877
Issue year2000
Vol54
No6
Pages995-999
ASJC Classification2700 General Medicine
DOIDOI:10.1054/mehy.1999.1006
URL http://www.sciencedirect.com/science/article/pii/S030698779991006X
Score (nominal)20
Score sourcejournalList
Publication indicators WoS Citations = 2; GS Citations = 4.0; Scopus SNIP (Source Normalised Impact per Paper): 2014 = 0.47; WoS Impact Factor: 2006 = 1.299 (2) - 2007=1.083 (5)
Citation count*4 (2015-04-09)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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