Dynamic T1 functional MRI examinations with use of blood pool contrast agent - an approach to optimization of the technique

Agata Majos , Tomasz Wolak , Michał Sapieha , Marek Olszycki , Piotr Bogorodzki , Ludomir Stefańczyk


The goal was to optimize dynamic T1 imaging for functional MRI (fMRI) examinations. For each of the 10 healthy subjects T1 3D gradient echo sequence (GRE) sequences were provided immediately after administration of blood pool contrast agent then every 2 h when subjects performed block finger tapings. Dynamic T1 fMRI is sensitive to detect cortical activations up to 6 h after BPCA administration. fMRI should be conducted within 2 h of CA administration, which is enough time for a typical fMRI experiment procedure.
Author Agata Majos
Agata Majos,,
, Tomasz Wolak RE
Tomasz Wolak,,
- The Institute of Radioelectronics
, Michał Sapieha
Michał Sapieha,,
, Marek Olszycki
Marek Olszycki,,
, Piotr Bogorodzki RE
Piotr Bogorodzki,,
- The Institute of Radioelectronics
, Ludomir Stefańczyk
Ludomir Stefańczyk,,
Journal seriesClinical Imaging, ISSN 0899-7071
Issue year2011
Keywords in EnglishBlood oxygenation level-dependent effect, CBV, Contrast media, Functional MRI
URL http://www.sciencedirect.com/science/article/pii/S0899707110002044
Languageen angielski
Score (nominal)15
Publication indicators WoS Impact Factor: 2011 = 0.746 (2) - 2011=0.782 (5)
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