Structure and physico-mechanical properties of low temperature plasma treated electrospun nanofibrous scaffolds examined with atomic force microscopy
Adrian Chlanda , Ewa Kijeńska , Chiara Rinoldi , Michał Tarnowski , Tadeusz Wierzchoń , Wojciech Święszkowski
AbstractElectrospun nanofibrous scaffolds are willingly used in tissue engineering applications due to their tunable mechanical, chemical and physical properties. Additionally, their complex openworked architecture is similar to the native extracellular matrix of living tissue. After implantation such scaffolds should provide sufficient mechanical support for cells. Moreover, it is of crucial importance to ensure sterility and hydrophilicity of the scaffold. For this purpose, a low temperature surface plasma treatment can be applied. In this paper, we report physico-mechanical evaluation of stiffness and adhesive properties of electrospun mats after their exposition to low temperature plasma. Complex morphological and mechanical studies performed with an atomic force microscope were followed by scanning electron microscope imaging and a wettability assessment. The results suggest that plasma treatment can be a useful method for the modification of the surface of polymeric scaffolds in a desirable manner. Plasma treatment improves wettability of the polymeric mats without changing their morphology.
|Journal series||Micron, ISSN 0968-4328, (A 25 pkt)|
|Publication size in sheets||0.5|
|Keywords in English||Atomic force microscopy, Surface modification, Electrospun fibers, RF plasma treatment, Tissue engineering, Nanomaterial|
|Score|| = 25.0, 25-04-2019, ArticleFromJournal|
= 30.0, 13-03-2019, ArticleFromJournal
|Publication indicators||= 8; = 7; : 2016 = 1.005; : 2017 = 1.728 (2) - 2017=2.013 (5)|
|Citation count*||13 (2019-08-17)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.