In vitro assessment of antibacterial properties and cytotoxicity of Al2O3‐Ag nanopowders
A M Jastrzębska , E Radziun , M Rosłon , A R Kunicki , A R Olszyna , J Dudkiewicz-Wilczyńska , E Anuszewska , Ewa Karwowska
AbstractAbstractThe present paper describes an In vitro assessment of the antibacterial properties and cytotoxic activity on mammalian cells of silver nanoparticles incorporated into an aluminium nano-oxide substrate produced by the thermal decomposition?reduction method. The Al2O3?Ag nanopowders show good bactericidal and fungicidal properties. An Al2O3?Ag (12·55 wt-\%) specimen at the concentration of 50 mg mL?1 reduced considerably the populations of Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Bacillus subtilis species, whereas the same nanopowder in a concentration of 90 mg mL?1 inhibited significantly the growth of P. aeruginosa, E. coli, S. aureus and Candida albicans and also significantly limited the number of B. subtilis. The Al2O3?Ag nanoparticles also showed no cytotoxic effects on the three selected cell lines, i.e. L929, BJ and HeLa, and the cells remained \\textgreater\75\% viability, as measured by MTT assay, and \\textgreater\102\% viability, obtained by EZ4U assay, relative to control at concentration as high as 200 ?g mL?1.
|Journal series||Advances in Applied Ceramics, ISSN 1743-6753, (A 30 pkt)|
|Keywords in English||Antibacterial, Cytotoxicity, Nanoalumina, Nanoparticles, Nanopowder, Nanosilver|
|Publication indicators||= 22; = 22; : 2011 = 0.83; : 2011 = 0.871 (2) - 2011=1.022 (5)|
|Citation count*||25 (2020-01-20)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.