The impact of transcription on posttranscriptional processes in yeast

Tomasz W. Turowski

Abstract

In eukaryotes, three RNA polymerases are responsible for transcription. These complex enzymes show many similarities with one another, such as several common or highly homologue subunits, while some other features, such as transcript length, diversity, processing, and transcription regulation, are unique to each polymerase. The present article reviews recent publications focusing on the impact of transcription of various RNA species in yeast on posttranscriptional steps such as pre-RNA processing, transport and decay. Two major conclusions emerge from a critical analysis of the current knowledge. (1) The kinetics of transcription elongation affects cotranscriptional pre-RNA processing. (2) The efficiency of transcription, by saturating the proteins interacting with RNA, indirectly affects the processing, export and decay of transcripts.
Author Tomasz W. Turowski (FC / IBC / DDTB)
Tomasz W. Turowski,,
- Department Of Drug Technology And Biotechnology
Journal seriesGene, ISSN 0378-1119
Issue year2013
Vol526
No1
Pages23-29
Publication size in sheets0.5
Keywords in EnglishTranscription, RNA processing, RNA decay, Maf1, rRNA, tRNA
DOIDOI:10.1016/j.gene.2013.04.021
URL http://www.sciencedirect.com/science/article/pii/S037811191300471X
Languageen angielski
File
1-s2.0-S037811191300471X-main.pdf 566.63 KB
Score (nominal)20
ScoreMinisterial score = 20.0, 28-11-2017, ArticleFromJournal
Ministerial score (2013-2016) = 20.0, 28-11-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2013 = 2.082 (2) - 2013=2.246 (5)
Citation count*2 (2015-11-15)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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