Electrochemical determination of lead ion with DNA oligonucleotide-based biosensor using anionic redox marker

Agnieszka Bala , Mariusz Pietrzak , Łukasz Górski , Elżbieta Malinowska

Abstract

The development of DNA-modified electrodes for the determination of lead cation is described. The performance of anionic (AQMS) and cationic (methylene blue) redox markers for this aim is compared. It is shown that the use of anionic marker results in a significantly better analytical parameters, as compared to measurements with cationic marker. The optimized sensor distinguishes itself with high selectivity towards lead cation and lower detection limit of 0.42 10−8 mol dm−3. The interaction between lead ion and DNA strands were studied using electrochemical impedance spectroscopy (EIS) and surface plasmon resonance with imaging (SPRi).
Author Agnieszka Bala (FC / IBC / DM)
Agnieszka Bala,,
- Department Of Microbioanalytics
, Mariusz Pietrzak (FC / IBC / DM)
Mariusz Pietrzak,,
- Department Of Microbioanalytics
, Łukasz Górski (FC / IBC / DM)
Łukasz Górski,,
- Department Of Microbioanalytics
, Elżbieta Malinowska (FC / IBC / DM)
Elżbieta Malinowska,,
- Department Of Microbioanalytics
Journal seriesElectrochimica Acta, ISSN 0013-4686, (A 40 pkt)
Issue year2015
Vol180
Pages763-769
Publication size in sheets0.5
Keywords in EnglishElectrochemical sensor; DNA-based biosensor; Metal ion determination
DOIDOI:10.1016/j.electacta.2015.08.162
URL http://www.sciencedirect.com/science/article/pii/S0013468615304102
Languageen angielski
File
1-s2.0-S0013468615304102-main.pdf 597.84 KB
Score (nominal)40
ScoreMinisterial score = 40.0, 28-11-2017, ArticleFromJournal
Ministerial score (2013-2016) = 40.0, 28-11-2017, ArticleFromJournal
Publication indicators WoS Impact Factor: 2015 = 4.803 (2) - 2015=4.721 (5)
Citation count*1 (2016-09-14)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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