Advanced trans-epithelial drug delivery devices

Tomasz Ciach , Aleksandra Mościcka-Studzińska

Abstract

The presented paper describes the drug delivery devices which can be considered as advanced or potentially "intelligent". Due to the current development state and the legal problems of implantable drug releasing electronic devices the review is limited to the systems which delivers drugs through the skin or mucosa. The article shows the principle of operation and some construction details of such devices. It also discusses the possible methods of sampling body fluids across the drug delivery barriers to introduce a feedback loop which is necessary to react on the metabolic process in the human body and their malfunctioning. In the near future presented devices will evolve towards the highly sophisticated systems which will monitor our metabolism and deliver necessary drugs and hormones in the precisely calculated doses to regulate our body functions without absorbing our attention.
Author Tomasz Ciach (FCPE / DBBE)
Tomasz Ciach,,
- Department of Biotechnology and Bioprocess Engineering
, Aleksandra Mościcka-Studzińska - [Warsaw University of Technology (PW), MNiSW [80]]
Aleksandra Mościcka-Studzińska,,
-
- Politechnika Warszawska
Journal seriesCurrent Pharmaceutical Biotechnology, ISSN 1389-2010, (A 30 pkt)
Issue year2011
Vol12
No11
Pages1752-1759
Publication size in sheets0.5
ASJC Classification3003 Pharmaceutical Science; 1305 Biotechnology
DOIDOI:10.2174/138920111798376978
URL http://europepmc.org/abstract/MED/21902629
Languageen angielski
Score (nominal)30
Score sourcejournalList
Publication indicators Scopus Citations = 2; WoS Citations = 2; Scopus SNIP (Source Normalised Impact per Paper): 2011 = 1.061; WoS Impact Factor: 2011 = 2.805 (2) - 2011=3.043 (5)
Citation count*2 (2020-01-13)
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* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.
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