Classification of amino acids and oligopeptides with the use of multi-mode chemical images obtained with ion selective electrode array
Patrycja Ciosek , Martyna Jańczyk , Wojciech Wróblewski
AbstractThe analysis of amino acids and oligopeptides as important bioanalytes is a significant task in medical diagnostics and proteomic research and currently it is based on chromatographic and electrophoretic methods. In this paper, an approach based on sensor array coupled with titration is proposed for effective recognition of 5 amino acids and 4 oligopeptides. It is shown, that the increase of information gained during measurements of sensors’ signals in various pH allows for capturing more data on interaction of amino acids and oligopeptides with various polymeric membranes of potentiometric electrodes used in the array, and that leads to the lowering of classification errors in partial least squares analysis.
|Journal series||Analytica Chimica Acta, ISSN 0003-2670|
|Keywords in English||Amino acids, Electronic tongue, Oligopeptides, Partial least squares-discriminant analysis, Sensor array|
|Publication indicators||: 2011 = 4.555 (2) - 2011=4.144 (5)|
|Citation count*||4 (2016-05-09)|
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perish system.