Computer aided movement analysis of MPTP mouse on inverted horizontal grid

Wiktor Niewiadomski , Ewelina Palasz , Małgorzata Skupińska , Marek Żyliński , Marta Steczkowska , Anna Gąsiorowska , Grażyna Niewiadomska , Gernot Riedel

Abstract

In rodents, the detection and quantification of mouse motor impairment caused by extensive loss of dopaminergic neurons is difficult. The inverted grid test, when mouse moved hanging under the mesh, was believed to be a challenging motor task involving forepaws, which would expose effects of dopaminergic lesions. This assumption was confirmed, however the evaluation of this test relied heavily on subjective rating.
Author Wiktor Niewiadomski
Wiktor Niewiadomski,,
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, Ewelina Palasz
Ewelina Palasz,,
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, Małgorzata Skupińska
Małgorzata Skupińska,,
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, Marek Żyliński (FM / IMBE) - [Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland]
Marek Żyliński,,
- The Institute of Metrology and Biomedical Engineering
- Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland
, Marta Steczkowska
Marta Steczkowska,,
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, Anna Gąsiorowska
Anna Gąsiorowska,,
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, Grażyna Niewiadomska
Grażyna Niewiadomska,,
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, Gernot Riedel
Gernot Riedel,,
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Journal seriesParkinsonism & Related Disorders, ISSN 1353-8020, (A 35 pkt)
Issue year2016
Vol22
Pages1-1
Publication size in sheets0.3
ConferenceXXI World Congress on Parkinson's Disease and Related Disorders, 06-12-2015 - 09-12-2015, Milano, Włochy
ASJC Classification2728 Clinical Neurology; 2717 Geriatrics and Gerontology; 2808 Neurology
DOIDOI:10.1016/j.parkreldis.2015.10.463
URL http://www.prd-journal.com/article/S1353-8020%2815%2900899-8/abstract
Languageen angielski
Not used for evaluationyes
Score (nominal)0
Score sourcejournalList
Publication indicators WoS Citations = 1; Scopus SNIP (Source Normalised Impact per Paper): 2016 = 1.288; WoS Impact Factor: 2016 = 4.484 (2) - 2016=4.38 (5)
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