Experimental evaluation of importance of the pulmonary surfactant for oxygen transfer rate in human lungs

Tomasz Robert Sosnowski , Leon Gradoń , Magdalena Skoczek , Hanna Droździel

Abstract

The rate of oxygen transport from atmospheric air into water and perfluorocarbon compound (PFC) was investigated. Static and dynamic systems with and without the presence of the lung surfactant monolayer were considered. For the case of water used as an oxygen absorbent, the monolayer activity allowed a simulation of the gas uptake into the lung hypophase. In the second case, a two-phase liquid system with water as a hypophase and PFC as the blood substitute simulated oxygen transport in the alveolus-blood system. Original experimental measurement devices gave the opportunity of determining the gas transport rate with the possibilities of indicating the role of the lung surfactant in the process and evaluating the influence of environmental conditions on the transport phenomena. Results of that work suggest a possible enhancing role of the lung surfactant in the oxygen transfer rate.
Author Tomasz Robert Sosnowski KIPZ
Tomasz Robert Sosnowski,,
- Chair of Integrated Process Engineering
, Leon Gradoń KIPZ
Leon Gradoń,,
- Chair of Integrated Process Engineering
, Magdalena Skoczek WIChiP
Magdalena Skoczek,,
- Faculty of Chemical and Process Engineering
, Hanna Droździel WIChiP
Hanna Droździel,,
- Faculty of Chemical and Process Engineering
Journal seriesInternational Journal of Occupational Safety and Ergonomics, ISSN 1080-3548
Issue year1998
Vol4
No4
Pages391-409
Publication size in sheets0.9
Keywords in Englishlung surfactant, blood oxygenation, perfluorocarbon compound
DOIDOI:10.1080/10803548.1998.11076401
URL http://www.tandfonline.com/doi/pdf/10.1080/10803548.1998.11076401?needAccess=true
Languageen angielski
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Sosnowski T.R. (i in.) - Experimental Evaluation of the Importance...pdf (file archived - login or check accessibility on faculty) Sosnowski T.R. (i in.) - Experimental Evaluation of the Importance...pdf 3.71 MB
Score (nominal)15
Publication indicators WoS Impact Factor: 2008 = 0.405 (2) - 2011=0.347 (5)
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